Sildenafil Citrate ( Viagra ) Male Enhancement Drugs Powder CAS 139755-83-2 Hormone
- Manufacturer: Dewael
- Product Assay: 99%+
- Appearance:white Crystalline powder.
- Place of Origin: China
- Certification: SGS,ISO9001,GMP
- Minimum Order Quantity: 10g
- Packaging Details: Discreet ways of packing for Customs pass guaranteed
- Delivery Time: Within 12 hours after receiving your payment
- Payment Terms: Western Union, MoneyGram,Bitcoin,Bank Transfer
- Shipping: EMS,DHL,Fedex,UPS,TNT and so on.
- Policy: Re-Shipping Policy
- Supply ability: 500-600kg/month
Sildenafil Citrate ( Viagra ) Male Enhancement Drugs Powder CAS 139755-83-2 Hormone
Quick details:
- Product Name:Sildenafil(viagra)
- Model NO.: Steroid Sex Enhance
- Customized: Customized
- Suitable for: Adult
- Purity: >99%
- Product Level: Medical/Pharmaceutical Level
- Reship Policy: Reship Free
- Shipment: TNT EMS, DHL ;FedEx
- Transport Package: Aluminum Foil Bag
- Origin: China
- Powder: Yes
- Certification: GMP, ISO 9001, USP, BP
- State: Solid
- Assay: 99%
- Devery Time: 5-7working Days Door to Door
- Payment Method: T/T,Western Union, Money Gram, Bank Transfer,Bitchcoin
- Specification: GMP
Sildenafil Citrate Description:
Sildenafil citrate, sold under Viagra, Revatio and various other trade names, is a medicament for the treatment of erectile dysfunction and pulmonary hypertension (PAH). It was originally made by Pfizer scientists David Bell, David Brown and Nikolay Twett.
The primary indication of sildenafil is the treatment of erectile dysfunction (unable to maintain a satisfactory erection to complete sexual intercourse). The currently used standard treatment methods include erectile dysfunction, including diabetes, by inhibiting cGMP-specific phosphodiesterase 5 (PDE5) to promote the regulation of penile blood flow in cGMP-degrading enzymes.
In addition to erectile dysfunction, sildenafil citrate can also be effective in rare pulmonary hypertension. It relaxes the arterial wall, leading to reduced pulmonary artery resistance and pressure. Which in turn reduces the workload of the right ventricle of the heart and improves the symptoms of right heart failure. Because PDE5 is mainly distributed in the smooth muscle of the arterial wall of the lung and penis, sildenafil has a selective effect in both regions without causing vasodilatation in other parts of the body. Pfizer submitted an additional registration of sildenafil to the US Food and Drug Administration (FDA), which was approved for use in June 2005. The preparation was named Revatio to avoid confusion with Viagra, 20 mg tablet for white round sildenafil plus bosentan and prostacyclin treatment regimens.
Sildenafil Citrate Applications:
1. Sildenafil citrate, sold as Viagra, Revatio and under various other trade names, is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). It was originally discovered by Pfizer scientists Andrew Bell, David Brown, and Nicholas Terrett.
2. The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction in all settings, including diabetes.
3. In clinical trials, the most common adverse effects of sildenafil use included headache, flushing, dyspepsia, nasal congestion and impaired vision, including photophobia and blurred vision.Some sildenafil users have complained of seeing everything tinted blue (cyanopsia).Some complained of blurriness and loss of peripheral vision. In July 2005, the FDA found that sildenafil could lead to vision impairment in rare cases and a number of studies have linked sildenafil use with nonarteritic anterior ischemic optic neuropathy.
4. Rare but serious adverse effects found through postmarketing surveillance include priapism, severe hypotension, myocardial infarction (heart attack), ventricular arrhythmias, stroke, increased intraocular pressure, and sudden hearing loss. As a result of these postmarketing reports, in October 2007, the FDA announced that the labeling for all PDE5 inhibitors, including sildenafil, required a more prominent warning of the potential risk of sudden hearing loss.
Sildenafil Citrate Recommend Dosage
Viagra (Sildenafil) at 50 mg or 100 mg significantly improved erection quality, treatment satisfaction, anxiety levels, and the sexual experience compared with placebo during DBPC.
Sildenafil 100 mg improved the sexual experience and treatment satisfaction, and reduced feelings of anxiety compared with the 50-mg dose.Viagra (Sildenafil citrate) 50 mg is the recommended starting dose for men with erectile dysfunction (ED); however, most men are later titrated to sildenafil 100 mg for improved efficacy.
COA:
Items | Specifications | Results |
Description | White crystalline powder | White crystalline powder |
Solubility | Souble in dimethylformamide,sparingly soluble in acetic acid and slightly soluble in methanol. | Conforms |
Identification by A) IR
B)Test for citrates |
The absorption maxima in the spectrum obtained with sample corresponds in position relative intensity to those in the spectrum obtained with sildenafil citrate CRS/working standard or with reference spectrum of sildenafil citrate.
To complies as per I.P |
Conforms |
Melting Range | Between 182 ℃ to 196 ℃ | 188 ℃-192 |
Water by KFR | NMT2.0% | 1.32%w/w |
Citric acid content | 28.0 to 34.0% w/w | 29.14w/w |
Loss on drying at 105 ℃ | NMT 1.0% w/w | 0.64%w/w |
Heavy metals | NMT 20 ppm | Conforms |
Sulphated ash | NMT 0.10% w/w | Conforms |
Related substance by HPLC | N-Oxide impurity NMT 0.50%
Chloro sulphonyl impurity NMT 0.20% Any other impurity NMT 0.30% Total impurities NMT 1.5% |
Not detected
Not detected 0.07% 0.20% |
Standard | USP32 |
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