Orally Anabolic Androgenic Steroids Dienogestrel / Dienogest CAS 65928-58-7
- Manufacturer: Dewael
- Product Assay: 99%+
- Appearance:White or Almost White Crystalline Powder
- Place of Origin: China
- Certification: SGS,ISO9001,GMP
- Minimum Order Quantity: 10g
- Packaging Details: Discreet ways of packing for Customs pass guaranteed
- Delivery Time: Within 12 hours after receiving your payment
- Payment Terms: Western Union, MoneyGram,Bitcoin,Bank Transfer
- Shipping: EMS,DHL,Fedex,UPS,TNT and so on.
- Policy: Re-Shipping Policy
- Supply ability: 500-600kg/month
Orally Anabolic Androgenic Steroids Dienogestrel / Dienogest CAS 65928-58-7
Product Details
Dienogestrel
Product Name: Dienogestrel
Synonyms: Dienogestrel;Dienogest;(17a)-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile;17a-Cyanomethyl-17-hydroxyestra-4, 9-dien-3-one;Dienogestril;Endometrion;STS 557;(17R)-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile
CAS: 65928-58-7
MF: C20H25NO2
MW: 311.422
Appearance: white powder
Package: 1KG/foil bag
Standard: Enterprise standard
Assay:99%
Grade: medical grade
Usage: Dienogest newly developed contraceptive drug, due to its strong inhibition of ovulation and used oral contraceptives.
Density: 1.2±0.1 g/cm3
Melting point: 210-214ºC
Boiling point: 549.0±50.0 °C at 760 mmHg
Flash point: 285.8±30.1 °C
storage temp. -20°C Freezer
Description:
Dienogest is used primarily as a contraceptive in combination with ethinylestradiol. It is given as a tablet containing 2 mg of dienogest and 30 μg of ethinylestradiol. Dienogest is also available in a quadriphasic oral contraceptive pill combined with estradiol valerate, marketed as Natazia in the United States and Qlaira in some European countries. This formulation is also approved for the treatment of heavy menstrual bleeding.The minimum dose required to inhibit ovulation has been found to be approximately 1 mg.Endometriosis Dienogest is also approved in the European Union for the treatment of endometriosis. It has been shown to be equally effective as leuprorelin, which is a second line medication against endometriosis.Dienogest newly developed contraceptive drug, due to its strong inhibition of ovulation and used oral contraceptives.
Applications:
(1) Dienogest has moderate affinity for the progesterone receptor in human uterus tissue, in vitro, about 10% that of progesterone.
(2) Inhibition of ovulation
The minimum effective dose of oral dienogest required to inhibit ovulation is 1 mg/day. The inhibition of ovulation by dienogest occurs mainly via peripheral action as opposed to central action on gonadotrophin secretion. Oral treatment of dienogest 2 mg/day in cyclical women reduced serum progesterone levels to anovulatory levels, however serum levels of lutenising hormone and follicle-stimulating hormone are not significantly altered.
Usage And Synthesis:
1.Derivative of 19-Nortestosterone. In combination with estrogen as oral contraceptive. Progestogen
2.Dienogest is an orally active synthetic progesterone (or progestin). It is available for use as an oral contraceptive in combination with ethinylestradiol. It has antiandrogenic activity and as a result can improve androgenic symptoms. It is a non-ethinyl
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