EP Standard White Estrogen Powder / Cyproterone Acetate CAS 427-51-0 Crystalline Powder
- Fabricante: Dewael
- Ensaio do produto: 99%+
- Aparência:Pó cristalino branco ou quase branco
- Lugar de origem: China
- Certificação: SGS,ISO9001, GMP
- Quantidade mínima de encomenda: 10g
- Detalhes de empacotamento: formas discretas de embalagem para Customs passagem garantida
- Tempo de entrega: Dentro 12 horas após o recebimento do pagamento
- Termos de pagamento: Western Union, MoneyGram,Bitcoin,Transferência bancária
- Remessa: EMS,DHL,Fedex,UPS,TNT e assim por diante.
- Política: Re-envio Política
- Capacidade de fornecimento: 500-600kg / mês
EP Standard White Estrogen Powder / Cyproterone Acetate CAS 427-51-0 Crystalline Powder
English Synonyms: 1,2-alpha-methylene-6-chloro-delta-(sup4,6)-pregnadiene-17-alpha-ol-3,20-dio;1,2-alpha-methylene-6-chloro-delta(sup6)-17-alpha-hydroxyprogesteroneacetat;1,2-alpha-methylene-6-chloro-pregna-4,6-diene-3,20-dione17-alpha-acetate;17-alpha-acetoxy-6-chloro-1-alpha,2-alpha-methylenepregna-4,6-diene-3,20-dio;20-dione,6-chloro-17-hydroxy-1-alpha,2-alpha-methylene-pregna-6-diene-3;6)-pregnadiene-17-alpha-ol-3,20-dione17-2-alpha-methylene-6-chloro-(sup4;6-chlor-delta(sup6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteronacetat;6-chloro-1,2-alpha-methylene-17-alpha-hydroxy-delta(sup6)-progesteroneaceta
CAS: 427-51-0
MF: C24H29ClO4
MW: 416.94
EINECS: 207-048-3
Padrão de qualidade: EP8
Grau: medical grade
Aparência: pó branco cristalino
Embalagem:1kg/saco de alumínio
Ensaio: 99%
Uso: Anti-androgen for the treatment of men with BPH, and can be used as male contraceptive
storage temp. 2-8° C
Densidade: 1.3±0.1 g/cm3
Ponto de fusão: 200-201ºC
Boiling point: 525.9±50.0 °C at 760 mmhg
flash point: 177.6±29.1 °C
Solubilidade: it is very soluble in dichloromethane, soluble in methyl alcohol, freely soluble in acetone, sparingly soluble in dehydrated alcohol, and insoluble in water.
Descrição:
O acetato de ciproterona (INN, USAN, BAN, JAN), sometimes abbreviated as CPA, and sold under brand names such as Androcur and Cyprostat, is a synthetic steroide antiandrogen drug with additional progestogen and antigonadotropic properties. Its primary action is to suppress the activity of the androgen hormones such as testosterone and its more potent metabolite dihydrotestosterone (DHT) in the body, effects which it mediates via competitive antagonism of the androgen receptor and inhibition of enzymes in the androgen biosynthesis pathway. The main therapeutic indications of cyproterone acetate are prostate cancer, benign prostatic hyperplasia, priapism, hypersexuality (por exemplo, as a form of chemical castration), and other conditions in which androgen action maintains the disease process. além do que, além do mais, it can also be used to treat acne and hirsutism in females, and is a common component in hormone therapy for transsexual women.
In addition to its antiandrogen properties, cyproterone acetate has weak progestogen activity (ou seja, it acts like progesterone). Accordingly, it can be used to treat hot flashes, and is also a component of some combined oral contraceptive pills such as Dianette in the United Kingdom and Diane-35 in other countries such as Canada. It is called Dixi-35 in Chile. No form of cyproterone acetate is available in the United States.
Until the development of leuprorelin, cyproterone acetate was one of the few drugs used to treat precocious puberty. It was also used in animal experimentation to investigate the actions of androgens in fetal sexual differentiation.
Dosagem:
Because of its pharmacokinetic properties, oral cyproterone and intramuscular injection of cyproterone acetate can be interchanged during long term treatment. If the side effects are unbearable, the dose can be reduced, but should be maintained at 100 para 300 mg per day in the oral range, or every two weeks intramuscularly 300 mg.
After oral or intramuscular injection, the plasma half-lives were 38 hours and 96 horas, respectivamente.
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