White Powder Cutting Cycle Steroids Estradiol Enantate 4956-37-0 Estrogen With Safe Delivery

1.Temel bilgiler.

Ürün adı:Estradiol Enanthate

CAS Number: 4956-37-0
Saflık: 99.5%
Moleküler ağırlık: 384.556
Moleküler formül: C25H36O3
Görünüm: Crystalline powder
Physical State: Solid
çözünürlük: Soluble in water (slightly).
Depolama: Store at room temperature
Erime Noktası: 94-96 °C
Boiling Point: ~509.5 ° C at 760 mmHg (Predicted)
Yoğunluk: ~1.1 g/cm3 (Predicted)

2.Product Description:

Estradiol enanthate (INN, USAN), or estradiol enantate, is a synthetic ester, specifically the 17-heptanoyl ester, of the natural estrogen, estradiol. It is marketed under the brand names Anafertin, Deladroxate, Perlutan, and Topasel, which are combination formulations of estradiol enanthate and dihydroxyprogesterone acetophenide, as a once-monthly injectable hormonal contraceptive in Spain and Latin America, and has been used as such since at least the mid-1960s.

Estradiol, veya daha doğrusu, 17β-estradiol, bir insan seks hormonu ve steroididir, ve birincil kadın seks hormonu. Adını östrus ve menstrüel kadın üreme döngülerinin düzenlenmesinde önemli olan bir maddeden alır.. Estradiol is essential for the development and maintenance of female reproductive tissues but it also has important effects in many other tissues including bone. Erkeklerde östrojen seviyeleri kadınlara göre daha düşük olmasına rağmen, östrojenlerin erkeklerde de önemli işlevleri vardır. Estradiol çoğu omurgalının yanı sıra birçok kabukluda da bulunur, böcekler, balık, ve diğer hayvan türleri.

Estradiol or oestradiol (American or British English usages), derives from estra-, Gk. οστρο? (oistros, literally meaning “verve or inspiration”) and -diol, a chemical name and suffix indicating that this form of steroid and sex hormone is a type of alcohol bearing two hydroxyl groups.

Estradiol özellikle dişi yumurtalıklarının foliküllerinde üretilir., ama aynı zamanda diğer endokrinlerde de (yani., hormon üreten) ve endokrin olmayan dokular (e.g., including fat, liver, adrenal, breast, and neural tissues). Estradiol is biosynthesized from progesterone (kolesterolden iki adımda ulaşıldı, ara pregnenolon yoluyla). Daha sonra bir temel yol, progesteronu 17-hidroksi türevine dönüştürür., and then to androstenedione via sequential cytochrome P450-catalyzed oxidations.Action of aromatase on this dione generates estrone, ve bir dehidrojenazın bunun üzerindeki etkisi başlık bileşiğini verir, 17β-estradiol.

3.Product Application:

When estrogen is prescribed for a woman with a uterus, progestin should also be initiated to reduce the risk of endometrial cancer. A woman without a uterus does not need progestin. Use of estrogen, alone or in combination with a progestin, should be with the lowest effective dose and for the shortest duration consistent with treatment goals and risks for the individual woman. Patients should be reevaluated periodically as clinically appropriate (e.g., 3-month to 6-month intervals) to determine if treatment is still necessary. For women who have a uterus, adequate diagnostic measures, such as endometrial sampling, when indicated, should be undertaken to rule out malignancy in cases of undiagnosed persistent or recurring abnormal vaginal bleeding.
Short-term cyclic use for treatment of moderate to severe vasomotor symptoms, vulval and vaginal atrophy associated with the menopause, the lowest dose and regimen that will control symptoms should be chosen and medication should be discontinued as promptly as possible.

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