EP Standard White Estrogen Powder / Cyproterone Acetate CAS 427-51-0 Crystalline Powder
- Fabricant: Dewael
- Essai de produit: 99%+
- Apparence:Poudre cristalline blanche ou presque blanche
- Lieu d'origine: Chine
- certificat: SGS,ISO9001, GMP
- Quantité minimum d'achat: 10g
- Détails de l'' emballage: des moyens discrets d'emballage pour la douane passer garanti
- Heure de livraison: Dans 12 heures après réception de votre paiement
- Modalités de paiement: Western union, MoneyGram,Bitcoin,Virement
- livraison: EMS,DHL,Fedex,UPS,TNT et ainsi de suite.
- Politique: Re-Politique de livraison
- Capacité d'approvisionnement: 500-600kg/mois
EP Standard White Estrogen Powder / Cyproterone Acetate CAS 427-51-0 Crystalline Powder
Anglais Les synonymes: 1,2-alpha-methylene-6-chloro-delta-(sup4,6)-pregnadiene-17-alpha-ol-3,20-dio;1,2-alpha-methylene-6-chloro-delta(sup6)-17-alpha-hydroxyprogesteroneacetat;1,2-alpha-methylene-6-chloro-pregna-4,6-diene-3,20-dione17-alpha-acetate;17-alpha-acetoxy-6-chloro-1-alpha,2-alpha-methylenepregna-4,6-diene-3,20-dio;20-dione,6-chloro-17-hydroxy-1-alpha,2-alpha-methylene-pregna-6-diene-3;6)-pregnadiene-17-alpha-ol-3,20-dione17-2-alpha-methylene-6-chloro-(sup4;6-chlor-delta(sup6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteronacetat;6-chloro-1,2-alpha-methylene-17-alpha-hydroxy-delta(sup6)-progesteroneaceta
CAS: 427-51-0
MF: C24H29ClO4
MW: 416.94
EINECS: 207-048-3
Norme de qualité: EP8
Qualité: medical grade
Apparence: Poudre cristalline blanche
Emballage:1kg/sac en aluminium
Essai: 99%
Usage: Anti-androgen for the treatment of men with BPH, and can be used as male contraceptive
storage temp. 2-8° C
Densité: 1.3±0.1 g/cm3
Point de fusion: 200-201ºC
Boiling point: 525.9±50.0 °C at 760 mmHg
flash point: 177.6±29.1 °C
Solubilité: it is very soluble in dichloromethane, soluble in methyl alcohol, freely soluble in acetone, sparingly soluble in dehydrated alcohol, and insoluble in water.
La description:
L'acétate de cyprotérone (INN, USAN, BAN, JAN), sometimes abbreviated as CPA, and sold under brand names such as Androcur and Cyprostat, is a synthetic steroide antiandrogen drug with additional progestogen and antigonadotropic properties. Its primary action is to suppress the activity of the androgen hormones such as testosterone and its more potent metabolite dihydrotestosterone (DHT) in the body, effects which it mediates via competitive antagonism of the androgen receptor and inhibition of enzymes in the androgen biosynthesis pathway. The main therapeutic indications of cyproterone acetate are prostate cancer, benign prostatic hyperplasia, priapism, hypersexuality (par ex., as a form of chemical castration), and other conditions in which androgen action maintains the disease process. En outre, it can also be used to treat acne and hirsutism in females, and is a common component in hormone therapy for transsexual women.
In addition to its antiandrogen properties, cyproterone acetate has weak progestogen activity (c'est-à-dire, it acts like progesterone). Accordingly, it can be used to treat hot flashes, and is also a component of some combined oral contraceptive pills such as Dianette in the United Kingdom and Diane-35 in other countries such as Canada. It is called Dixi-35 in Chile. No form of cyproterone acetate is available in the United States.
Until the development of leuprorelin, cyproterone acetate was one of the few drugs used to treat precocious puberty. It was also used in animal experimentation to investigate the actions of androgens in fetal sexual differentiation.
Dosage:
Because of its pharmacokinetic properties, oral cyproterone and intramuscular injection of cyproterone acetate can be interchanged during long term treatment. If the side effects are unbearable, the dose can be reduced, but should be maintained at 100 à 300 mg per day in the oral range, or every two weeks intramuscularly 300 mg.
After oral or intramuscular injection, the plasma half-lives were 38 hours and 96 heures, respectivement.
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