Avanafil CAS: 330784-47-9 For Therapy Of Male Sex Enhancement White Powder

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Nome do produto :	Avanafila
Ensaio :	99% min.
CAS:	330784-47-9
Fórmula molecular:	C23H26ClN7O3
Peso molecular:	483.95
Ponto de fusão:	150-152° C
Densidade:	1.372
MF:
Storage condition:	Refrigerator
Personagem:	White to Off-White Cyrstalline Solid.
Uso:	Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
categorias:	Active Pharmaceutical Ingredients; Cnbio; Erectile Dysfunction; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; APIs.

Avanafil Description:

Avanafil is an oral drug that is used for treating impotence (the inability to attain or maintain a penile erection), also known as erectile dysfunction (ED).

It is in a class of drugs called phosphodiesterase inhibitors that also includes tadalafil (Cialis), sildenafil (Viagra) and vardenafil (Levitra). Erection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis, e, at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis.

Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the penis.

Advantage of Avanafil:

This medication’s advantage is that it works much faster than other erection-inducing drugs. Por exemplo, Viagra generally takes about an hour to induce a good erection, and probably longer than that if the man has a lot of food in his stomach.
Cialis and Levitra also tend to take about an hour to work. This type of delay can make it rather difficult to enjoy a really spontaneous sex life.
Em contraste, avanafil is absorbed very rapidly. It reaches a maximum bloodstream concentration in under 45 minutos. It is said that most men can get an erection with 15 minutes of swallowing the tablet.

How Does Avanafil Work?

Erection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis, e, at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis. Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the penis. The nitric oxide causes an enzyme, guanylate cyclase, to produce cyclic guanosine monophosphate (cGMP). It is cGMP that is primarily responsible for increasing and decreasing the size of blood vessels carrying blood to and from the penis, respectivamente, and causing an erection. When the cGMP is destroyed by another enzyme, phosphodiesterase-5, the blood vessels return to their normal size, blood leaves the penis, and the erection ends. Avanafil prevents phosphodiesterase-5 from destroying cGMP so that cGMP stays around longer. The persistence of cGMP leads to a more prolonged engorgement of the penis with blood. Avanafil was approved by the FDA in April 2012.

How to Take Avanafil:

Take avanafil exactly as your doctor tells you to. It is intended to be taken before sexual activity – it is NOT for continuous daily use. You should take one tablet about 15-30 minutes before you plan to have sex. You can take the tablet either before or after food but, if you have just eaten a meal, it may take longer for it to work.

There are three strengths of avanafil tablets: 50 mg, 100 mg and 200 mg. It is likely that you will be given the 100 mg strength tablet to begin with, but this may be changed subsequently depending upon how you react. Each time you collect a prescription, check to make sure it contains the strength of tablet you are expecting.
Do not take more than one dose of avanafil in any 24-hour period.

Avanafil COA

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