Top Quality Weight Loss Chemical Raw Material Levothyroxine Sodium / T4 Powder CAS: 51-48-9
- Manufacturer: Dewael
- Product Assay: 99%+
- Appearance:White Crystalline Solid.
- Place of Origin: China
- Certification: SGS,ISO9001,GMP
- Minimum Order Quantity: 10g
- Packaging Details: 1 kg/foil bag,25kg/drum or as your requirements
- Delivery Time: Within 12 hours after receiving your payment
- Payment Terms: Western Union, MoneyGram,Bitcoin,Bank Transfer
- Shipping: EMS,DHL,Fedex,UPS,TNT and so on.
- Policy: Re-Shipping Policy
- Supply ability: 500-600kg/month
Top Quality Weight Loss Chemical Raw Material Levothyroxine Sodium / T4 Powder CAS: 251-48-9
Details:
Product name:Levothyroxine Sodium / T4
CAS: 51-48-9
Einecs: 200-101-1
MF: C15H11I4NO4
MW: 776.87
Standard : USP30
Grade : Pharmaceutical Grade
Appearance :White Crystalline Solid
Storage: Shading, confined preservation
Usage :One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the people.
COA:
| Item | Specification | Result |
| Appearance | An odorless, almost white or buff colored powder | pass |
| Solubility | 1,Very slightly soluble in water | pass |
| 2,slightly soluble in alcohol | pass | |
| 3,practically insoluble in most other organic solvents | pass | |
| 4,disolves in diluted aqueous sodium hydroxide solutions | Pass | |
| Identificaton | a) Heat about 50 mg with a few drops of sulfuric acid in a porcelain crucible: violet vapors of iodine are evolved. | pass |
| b)The retention time of the major peak is confirm to the RS | pass | |
| Loss on Drying | Not more than 4.0% | 0.46% |
| [a]20/D
C=1 in 1M HCl/EtOH 1:4 |
+18 ~ +22o | ＋20.9o |
| Assay(HPLC) | Not less than 95.0% | 99.18% |
| Levothyroxine sodium | Not more than 5.0% | 0.68% |
| Conclusion: | Up to the Standard for Export | |
Description:
Levothyroxine (INN, USAN) or L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated cholesterol levels) but was withdrawn due to cardiac side effects.
Levothyroxine is typically used to treat hypothyroidism, and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy. It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing. Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.
Application:
Levothyroxine for systemic administration is available as an oral tablet, an intramuscular injection and as a solution for intravenous infusion. Furthermore, levothyroxine is available as both brand-name and generic products. While the United States Food and Drug Administration (FDA) approved the use of generic levothyroxine for brand-name levothyroxine in 2004, the decision was met with disagreement by several medical associations.
Levothyroxine is typically used to treat hypothyroidism,and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy.It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing.Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.
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