99% High Purity Local Anesthetic Drugs Propitocaine Hydrochloride CAS 1786-81-8 Prilocaine for Pain Relief
- Fabrikant: Dewael
- product Assay: 99%+
- Uiterlijk:wit kristallijn poeder.
- Plaats van herkomst: China
- certificaat: SGS,ISO9001, GMP
- Minimum bestelhoeveelheid: 10g
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- Capaciteit van de levering: 500-600kg / maand
99% High Purity Local Anesthetic Drugs Propitocaine Hydrochloride CAS 1786-81-8 Prilocaine for Pain Relief
Product details:
productnaam | Propitocaine hydrochloride |
Synoniemen | 2-(propylamino)-o-propionotoluidide hydrochloride;2-(propylamino)-o-propionotoluididmonohydrochloride;alpha-propylamine-2-methyl-propionanilidehydrochloride;citanesthydrochloride;l-67hydrochloride;n-(2-methylphenyl)-2-(propylamino)-propanamidmonohydrochloride;prilocainechloride;xylonest |
CAS |
1786-81-8
|
MF | C13H21ClN2O |
MW | 256.77 |
EINECS | 217-244-0 |
Productcategorieën | Active Pharmaceutical Ingredients;Sodium channel;Amines;
Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;RULIDE |
MP | 168-170° C |
Storage temp. | Refrigerator |
Chemical Propertie |
Witte vaste stof
|
Puurheid |
99%
|
Gebruik |
Antibacterial , Anesthetic
|
M.S. | ![]() |
Beschrijving:
Propitocaine hydrochloride is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia. In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue.
Propitocaine is a local anaesthetic used in the form of a hydrochloride to relieve the pain of skin. This compound is a componebt of skin patch products. Prilocaine is a local anesthetic of the amino amide type. Prilocaine is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/pril ocaine or EMLA), for treatment of conditions like paresthesia. Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other sid. The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into para-aminobenzoic acid. Amide is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain), Chloroprocaine (Nesacaine), Tetracaine (Pontocaine), Benzocaine, Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest), Bupivacaine (Marcaine), Etidocaine (Duranest) .
COA:
Productnaam
|
Prilocaine hydrochloride | ||
CAS | 1786-81-8 | Outer Packing | 25kgs |
Production date
|
2018.02.12 |
Houdbaarheid
|
2020.02.11 |
Standard adopted
|
USP36 | ||
Items of analysis
|
Specificaties
|
Resultaten | |
Beschrijving | Wit kristallijn poeder | Voldoet | |
oplosbaarheid | Freely soluble in water and in alcohol ,slightly soluble in chloroform,very slightly soluble in acetone; practically insoluble in ether | Voldoet | |
Identificatie | By IR absorption,Om aan te passen aan de werkstandaard | Voldoet | |
Identificatie | Should be positive response | Voldoet | |
Identificatie | Should display the reaction of chloride differentiated | Voldoet | |
Smeltpunt | 166~169℃ | 166~168℃ | |
Verlies bij drogen | ≤ 0.3% | 0.13% | |
Residu bij ontsteking | ≤0,1% | 0.03% | |
Zware metalen | ≤0.002% | <0.002% | |
Resterende oplosmiddelen | Should be to match with the standard | Voldoet | |
analyse | 99.0% ~101.0%(on the anhydrous basis ) | 99.46% | |
Conclusie
|
Qualified |
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