Female Synthetic Hormone Nafarelin Acetate (synarel) 76932-56-4 for Treating Endometriosis
- Fabrikant: Dewael
- product Assay: 99%+
- Uiterlijk:White lyophilized powder
- Plaats van herkomst: China
- certificaat: SGS,ISO9001, GMP
- Minimum bestelhoeveelheid: 100ml
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- Capaciteit van de levering: 500-600Liter/maand
Female Synthetic Hormone Nafarelin Acetate (synarel) 76932-56-4 for Treating Endometriosis
Nafarelin Acetate (synarel) Details:
Productnaam | Nafarelin Acetate |
CAS NO. | 76932-56-4 |
Synoniemen | Nafarelin Acetate |
Category | Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals. |
Puurheid | 99% Nafarelin Acetate |
Uiterlijk | Nafarelin Acetate powder |
Houdbaarheid | 2 years for Nafarelin Acetate |
Gebruik | Nafarelin Acetate is used in female infertility and endometriosis. |
opslagruimte | Nafarelin Acetate should be stored in a well-closed containerat low temperature, keep away from moisture, heat and light. |
Beschrijving
Its proposed mechanism of action could be the desensitization of pituitary GnRH receptors resulting in a decrease in gonadotropin release, and ovarian hormone serum concentrations much like those achieved in postmenopausal women. Nafarelin is administered by nasal inhalation and contains been generally well tolerated. It is associated with a high incidence of adverse effects but they are rarely severe enough to cause withdrawal from treatment, the ones occurring most frequently–hot flashes, vaginal dryness, and decreased libido–are a result of the hypoestrogenemia induced through the drug. Increased bone turnover is situated women on nafarelin but biochemical parameters resume pretreatment concentrations by six months after termination of treatment. This agent’s invest the therapy of endometriosis will be determined as clinical experience accumulates.
Nafarelin Acetate Application:
Treating endometriosis, including relieving pain and reducing lesions. It is usually used to treat early puberty (central precocious puberty [CPP]) in children of both sexes. It could be used for other difficulties as determined by your doctor.
Nafarelin is really a gonadotropin-releasing hormone (GnRH) agonist. It functions by decreasing creation of certain steroids in your body, which decreases the symptoms of endometriosis or early puberty.
COA
Item | Specificatie | Result |
Uiterlijk | White powder | Voldoet |
Identificatie | Positief | Voldoet |
analyse | 98.0% min | 98.2% |
Loss on Drying | 6.0%maximaal. | 5.8% |
Acetate Content(door HPLC) | 10.0%maximaal. | 9.8% |
Peptide Content (N%) | 80.0%min. | 88.0% |
Amino Acid Composition | ±10% of theoretical | Voldoet |
Single Impurity (HPLC) | 1.0%maximaal. | 0.45% |
MS(ESI) | Consistent | Voldoet |
Mass Balance | 95.0~105.0% | 98.0% |
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