Drospirenone Female Sex Hormones for Preventing Pregnancy CAS 67392-87-4

Basic Info.

Nom du produit: Drospirenone
Synonymes: arbolactone
CAS: 67392-87-4
MF: C24H30O3
MW: 366.49
EINECS: 266-679-2
MP: 196-200° C
Alpha: -180°(c=0.5, chloroform)
Storage temp: -20°C Freezer
Apparence: Off-White Crystalline Powder

Product Description:

Maintenant, the only similar characteristics with natural progesterone progesterone progesterone structure with traditional oral contraceptives contained completely different, it is closer to natural progesterone. Drospirenone addition to anti-androgen effect, but also has the role of Salt corticosteroids can prevent sodium and water retention in the body. Not only has excellent contraceptive effect, there will be many positive effects on women’s health. Par exemple, to reduce the acne, skin is more smooth, effective control of body weight.

Product Application:

Drospirenone is an ingredient in some birth control pills and hormone replacement therapy. In combination with ethinyl estradiolit is used as contraception, and for women who want contraception it is also approved by the U. S. Food and Drug Administration(FDA) to treat moderate acne and premenstrual dysphoric disorder.

Medical uses

Drospirenone is an ingredient in some birth control pills and hormone replacement therapy. In combination with ethinylestradiol it is used as contraception, and for women who want contraception it is also approved by the U.S. Food and Drug Administration (FDA) to treat moderate acne and premenstrual dysphoric disorder.

Drospirenone is 8–10 times more potent as an antimineralocorticoid relative to spironolactone (3 mg drospirenone is equivalent to about 20–25 mg spironolactone in this regard. It is more potent as an antiandrogen relative to spironolactone also but is less potent relative to cyproterone acetate, having about one-third the potency of this drug. Progestogenic, antimineralocorticoid, and mild antiandrogenic effects have been observed in humans during treatment with drospirenone at a dosage range of 0.5 à 4 mg per day orally. The antimineralocorticoid properties exhibited by drospirenone promote sodium excretion and prevent water retention.

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