Pharmaceutical Raw Materials Steroid Dyclonine Hydrochloride CAS 536-43-6 for Health Care
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Pharmaceutical Raw Materials Steroid Dyclonine Hydrochloride CAS 536-43-6 for Health Care
Βασικές πληροφορίες.
English name: Dyclonine Hydrochloride
Other Name: Dyclonine, Hydrochloride; 4-butoxy-3-piperidinopropiophenone hydrochloride; Dyclonine HCL
CAS: 536-43-6
EINECS Number: 208-633-6
Formula: C18H28ClNO2
MW: 325.8734
Boiling point: 424.5 ° C at 760 mmHg
Flash Point: 210.5 ° C
Vapor Pressure: 2.06μι-07mmHg at 25 ° C
Uses:For topical anesthesia
Χημική δοκιμή:99.72%
Εμφάνιση:white powder
Περιγραφή
Dyclonine hydrochloride (Dyclonine hydrochloride), also known as dicyclone, chemical name 4 – butoxy – β – piperidinyl phenylacetone hydrochloride, as a quick onset, the role of a long time, adverse reactions, safety High local anesthetic. Στο παρόν, the domestic market has been reported or reported Dacronine hydrochloride formulations are mainly ointment, cream, liniment, solution, gel and emulsion type mortar. Among them, the first five are mainly external use, the last one is for endoscopy, digestive tract and other endoscopic examination. Clinical application of mucosal surface anesthesia and skin analgesia, itching.
Dyclonine is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt. Dyclonine hydrochloride has been found to possess, in addition to its topical anesthetic properties, significant bactericidal and fungicidal activity. Selfsterilizing action manifested by preparations containing the drug was considerably enhanced upon the addition of chlorobutanol. Results of in vitro tests employing microorganisms commonly involved in local infections indicated that the two agents in combination act synergistically.
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Εφαρμογή
This product should be formulated as a 1% cream, ointment or 0.5 να 1% of the agent, trauma, insect bites hurt a few kinds of skin itching symptoms of pain that is excellent itching, bactericidal anti-inflammatory effect. It can also be used to control a variety of allergy symptoms.
Προσδιορισμός
Είδη | Προδιαγραφές | Αποτελέσματα |
Εμφάνιση | A white or almost white crystalline | A white powder |
Αναγνώριση | A,σι,C in Pass | Συμμορφώνεται |
Σημείο Τήξης | 173 – 178 ºC | 174-177.5ºC |
Acidity(ΡΗ) | 4.0 – 7.0 | 6.6 |
Απώλεια κατά το στέγνωμα | ≤ 1.0 % | 0.33 % |
Υπολείμματα κατά την ανάφλεξη | ≤ 0.2 % | 0.034% |
Χημική δοκιμή | 98 – 102 % | 99.72% |
CONCLUSION | Pass USP 34 |
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